Tidbits from the above sources:
Geoff Keighley: "Tell us a bit about the state of development, I think a lot of fans yesterday were thinking is this really coming out next year, etc"
Mac Walters: "We are very much in the final stretch of development..." "...we want to show assets that are as amazing as possible" "right now it's polish, polish, polish".
As for why BioWare and EA chose not to show more of Mass Effect: Andromeda, both Walters and Flynn were upbeat.
Right after the EA press conference, Mass Effect 1 and 2 lead artist Johnathan Cooper raised eyebrows by suggesting the lack of gameplay footage meant Andromeda was having a troubled development.
"There's definitely more stuff we could have shown or talked about," Flynn replied. "But now we're shipping next spring, the time to really blast all that out there is after the other games come out. We'll be there then to have a great big reveal and release all the details."
BioWare has since confirmed that we won't see more of Andromeda now until next November, and the franchise's annual N7 Day celebrations. "[Development] is healthy," Flynn concluded. "Dragon Age: Origins was six years. Star Wars: The Old Republic was six years. The original Mass Effect was four. Maybe we're just not the fastest at this!"
"We acknowledged it in the endings of Mass Effect 3 and I think that's where we want to leave it for now," Flynn said.
"We want this to be a new story and it would be very hard to say it's a new story but also that you need to understand how [the past trilogy] ended." Andromeda's setting, naturally places it beyond the Milky Way-changing consequences of Mass Effect 3's explosive finale.
Each of the options available to players were spread across our galaxy via the Mass Relays - but no further. By moving geographically beyond the reaches of this choice, BioWare has also negated the need for a canon ending.
But there was still an expectation among many fans that Andromeda would make mention of the endings in some way as it is set chronologically afterwards. However, that time difference goes away when you consider "how long it takes to travel between galaxies", Walters suggested.